The endogenous cannabinoid system is absolutely essential to the health of the individual. Thanks to this system, cannabis has medical benefits for them human species. The endogenous cannabinoid is a receptive system with the most receptors compaired to any other system in the body. This system regulates your sleep, hunger, overexcitement etc. It is the only receptor system which can communicate two ways and not only send signals one way.
Medical cannabis is indeed a historical medicine. We can find reports of its use in the history of ancient China, where it was “prescribed” by the Emperor Shen Neng almost 3000 years BC, at least according to Chinese legends. For example, patients with rheumatism, malaria, or bad memory at that time could have made a healing tea for themselves without fear. It is from China that cannabis has gradually spread throughout the world, and one of the most important things is our endocannabinoid system, which makes it possible for cannabis to act in synergy with our body.
In this article, we will try to describe this system in the best way possible. At least partly to shed light on the mechanism, by which cannabis is able to treat such a wide range of diseases.
History of endocannabinoid system
All species of today’s vertebrates on our planet share this endogenous cannabinoid system that allows us to continually adapt to the changing environment. Current science estimates that this system has evolved in primitive animals about 600 million years ago.
You may think we know everything about the endocannabinoid system today, from A to Z. Since the discovery of this system, in the mid-1990s, only 20 years have passed by Israeli doctor Raphael Mechoulam (who first identified and named THC). Over the past 20 years, more than 20,000 scientific publications have been published on this subject, which means on avarage 2 studies per day. However, it is true that even this number of studies is only a highlight of the whole issue of the endocannabinoid system.
Endogenous Cannabinoid System
Dr. Dustin Sulak of the Maine Medical Clinic, Massachusetts, USA, who worked with his colleagues to continue to treat more than 1,800 cancer patients, Crohn’s disease, epilepsy, chronic pain, sclerosis, insomnia, Tourette’s syndrome, eczema and many other diseases, highlights the following:
“The so-called endogenous cannabinoid system, named aptly by the plant that has been discovered, is perhaps the most important physiological system responsible for both the production and maintenance of human health.”
Endocannabinoids and their receptors can be found throughout the body: in the brain, organs, connective tissues, glands, and cells of the immune system. In each of these body parts, cannabinoids work in different ways, but the goal is always the same: so-called homeostasis, maintaining a stable indoor environment across external fluctuations. “
Cannabinoids promote homeostasis at every level of biological life, from subcellular to whole organisms, and possibly even across society. One example is the so-called autophagy, a process in which a cell is able to isolate portions of its contents, “digest” them, and recycle them for further use. This whole process is mediated by the endocannabinoid system. While this process allows healthy cells to maintain a steady process of synthesis, degradation and subsequent recycling, it has exactly the opposite effect on cancer cells: they program their cell death, resulting in the promotion of homeostasis and the survival of healthy cells throughout the body.